5-Alpha Reductase Deficiency: A Review of Five Cases Diagnosed with Ambiguous Genitalia
نویسندگان
چکیده
منابع مشابه
Ambiguous genitalia and intersex.
Intersex disorders are rare congenital malformations with over 80% being diagnosed with congenital adrenal hyperplasia (CAH). It can be challenging to determine the correct gender at birth and a detailed understanding of the embryology and anatomy is crucial. The birth of a child with intersex is a true emergency situation and an immediate transfer to a medical center familiar with the diagnosi...
متن کاملSide Effects of 5-Alpha Reductase Inhibitors: A Comprehensive Review.
INTRODUCTION 5α-reductase inhibitors (5ARI) include finasteride and dutasteride, and are commonly prescribed in the treatment of benign prostatic hyperplasia and androgenic alopecia. 5ARIs are associated with several known adverse effects (AEs), with varying reported prevalence rates. AIM The aim was to review and summarize findings from published literature detailing AEs associated with 5ARI...
متن کاملa review of patients with ambiguous genitalia due to congenital adrenal hyperplasia
to review the diffrent aspects of gender, subtype of cah, management and results in all our patients with ambiguous genitalia diagnosed as congenital adrenal hyperplasia during the past 30 years. methods: the files of all our patients with cah reviewed retrospectively. results: out of 256 patients who had ambiguous genitalia due to cah, 96% were female and 4% were male. 21-ohd was diagnosed in ...
متن کاملAmbiguous genitalia, impaired steroidogenesis, and Antley-Bixler syndrome in a patient with P450 oxidoreductase deficiency.
Cytochrome P450 oxidoreductase deficiency is a recently established autosomal recessive disease characterised by ambiguous genitalia, impaired steroidogenesis, and skeletal malformations, referred to as Antley-Bixler syndrome. Clinical manifestations in affected patients are highly variable. We report on a girl with P450 oxidoreductase deficiency who presented with virilisation at birth. There ...
متن کاملEarly assessment of ambiguous genitalia.
T o discover that there is uncertainty about the sex of one’s newborn baby is devastating and often incomprehensible for most parents. It is paramount that clear explanations and investigations are commenced promptly, and that no attempt is made to guess the sex of the baby. Extreme sensitivity is required, and ideally the baby should be managed in a tertiary centre by a multidisciplinary team ...
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ژورنال
عنوان ژورنال: The Turkish Journal of Endocrinology and Metabolism
سال: 2017
ISSN: 1301-2193,1308-9846
DOI: 10.25179/tjem.2017-56481